Compared with the normal group, the CML group showed a higher infiltration of the activated CD4+ memory T cells, activated NK cells, monocytes, accompanied by the low infiltration of Plasma cells, resting Mast cells, T cells regulatory, Macrophages M0, Macrophages M2, Dendritic cells and Neutrophils (Figure 3B). The gene discussed is CD4; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.