The results unveiled intriguing correlations: ART1 expression exhibited negative correlations with THYM (P = 0.03), ALL (P = 0.02), and GBM LGG (P < 0.001), while showcasing positive correlations with NB (P = 0.03), LAML (P < 0.001), WT (P = 0.04), PAAD (P = 0.001), BRCA (P = 0.01), KIRP (P = 0.01), COAD (P < 0.001), COADREAD (P < 0.001), PRAD (P < 0.001), LUSC (P < 0.001), STAD (P < 0.001), STES (P < 0.001), KIPAN (P < 0.001), and HNSC (P < 0.001) (Supplementary Figure 3A). Here, ART1 is linked to acute lymphoblastic leukemia.