GGT7 and pancreatic adenocarcinoma: In conclusion, our study demonstrated a novel role for TXNDC12 in the regulation of ferroptosis through interaction with GGT7 and GSH metabolism, and the study of the biological function and potential molecular mechanisms of TXNDC12 in PAAD could provide a theoretical basis and experimental rationale for the development of new bioprosthetic markers or the development of targeted drugs in PAAD.