The results showed that PLBD1 was significantly enriched in high-grade glioma (especially GBM), non-1p/19q deletion status and IDH wild-type in TCGA (Figure 5A, D, G), CGGA-693 (Figure 5B, E, H) and CGGA-325 datasets (Figure 5C, F, I). The gene discussed is PLBD1; the disease is glioblastoma.