ATG16L1 and Familial prostate cancer: A potential role of decreased autophagy in promoting prostate cancer progression has been suggested through correlations between low prostate tumour expression of the core ATG genes FIP200, ATG16L1, or GABARAPL1 and poor prognosis in clinical prostate cancer cohorts (Li et al., 2014; Huang et al., 2015; Su et al., 2017).