NFKB1 and alkaline phosphatase measurement: In contrast to the aforementioned cytokines, IL-10 is an anti-inflammatory cytokine that is produced by M2 macrophages, T-cells, B-cells and dendritic cells to combat the production of inflammatory mediators via inhibiting NFκB activation, and aid the regeneration phase of the pancreas after AP (Mahony et al., 2016).