CD4 and pulmonary fibrosis: Full b-cell depletion by 7th day. Restoration of CD4+ T cells on day 37 IgG levels did not drop below 700 mg/dL ANA reactivity fell to 0. Fibroblast activation decreased in myocardium (32.6%). Pulmonary fibrosis did not progress. Carpal arthritis improved after 3 months. Tender joint counts decreased from 22 to 3 EUSTAR activity was 0. Raynaud’s phenomenon attack frequency reduced. Skin fibrosis improved.