NCM 1921, a mixture contain beef tallow among other fats, has potential as a therapeutic agent for atopic dermatitis, potentially serving as a replacement for corticosteroids or as a adjunct treatment. NCM 1921 improves symptoms, suppresses dermal lesions, reduces inflammatory cells, lowers IgE levels, regulates T cell response, and enhances skin barrier function. Here, IGHE is linked to atopic eczema.