SCCHN - head and neck squamous cell carcinoma; OS - overall survival; ORR - objective response rate; CR - colorectal cancer; PFS - progression-free survival; DOR - duration of response; EGFR - epidermal growth factor receptor; NSCLC - non-small cell lung cancer; MET - mesenchymal-epithelial transition; MOA - mechanism of action; ADCC - antibody-dependent cellular cytotoxicity; ADCP - antibody-dependent cellular phagocytosis; ADCR - antibody-dependent cytokine release; ADCT - antibody-dependent cellular trogocytosis; CRC - colorectal cancer. The gene discussed is EGFR; the disease is non-small cell lung carcinoma.