Subsequent laboratory tests for serological biomarkers associated with SLE include antigen-specific antinuclear antibody (ANA), with positive results prompting additional testing targeting double-stranded DNA (dsDNA) or ribonucleoprotein (RNP) complexes (Ro/SSA, La/SSB, Smith, and RNP) [1]. Here, CALR is linked to systemic lupus erythematosus.