Bergstrand et al. [84, 85] also demonstrated some significant metastasis-related proteins in platelets that co-culturing platelets with various cancer cell lines induced distinct clustering patterns include P-selectin, angiogenesis-regulating proteins and SNAREs (soluble N-ethylmaleimide factor attachment protein receptors) involved in cancer cell interactions (Fig. 3F, G). This evidence concerns the gene SELP and cancer.