To further clarify the relationship between LINC00987 and HMGA2 in ADR-resistant AML cells, si1-LINC00987 and pcDNA-HMGA2 were co-transfected into ADR/MOLM13 and ADR/HL-60 cells and then treated with 0.2 μM ADR. The gene discussed is HMGA2; the disease is acute myeloid leukemia.