Nevertheless, we did not observe the causal associations of other genetic mimicry drug targets (NPC1L1, PCSK5, ABCG5/ABCG8, APOB, LDLR, LPL, APOC3 and CETP) and RA, neither did the genetically proxied drug targets (HMGCR, NPC1L1, PCSK5, ABCG5/ABCG8, APOB, LDLR, LPL, APOC3 and CETP) inhibition and SLE, MS, CD and UC (Table S16-23). Here, HMGCR is linked to systemic lupus erythematosus.