GPX4 and cancer: FSP1 gene disruption [50,52] or chemical inhibition [51,[98], [99], [100]] sensitizes cancer cells to other ferroptosis inducers (e.g., GPX4 inhibitors or endoperoxide-containing ferroptosis inducers), but FSP1 inhibition is typically not sufficient on its own to induce ferroptosis in cultured cancer cells [50,51,[98], [99], [100]].