Comparison of Jäkel et al.43 with our study revealed that control-related oliglia0 most closely resembled highly myelinating OPALIN+ cells from Jäkel6 (Extended Data Fig. 8a–c), while ALS-associated oliglia1 and oliglia4 aligned to not-actively myelinating Jäkel1 (Extended Data Fig. 8d–h). The gene discussed is OPALIN; the disease is amyotrophic lateral sclerosis.