ACLY and nonpapillary renal cell carcinoma: Enzymes involved in the intrinsic FFA metabolism pathway include FFA synthase, acetyl-CoA carboxylase, ATP citrate lyase, stearoyl-CoA desaturase 1, carnitine palmitoyltransferase 1 A and the perilipin family, and each might be potential therapeutic targets in ccRCC owing to the link between lipid deposition and ccRCC risk [3, 27].