Among these isoforms, MT1G, a newly identified member of the MT1 family in humans, has been linked to ferroptosis in various cancers, including colorectal cancer, hepatocellular carcinoma (HCC), esophageal adenocarcinoma, prostate cancer, pancreatic adenocarcinoma, glioblastoma, and osteosarcoma [6–12]. The gene discussed is MT1G; the disease is osteosarcoma.