To further clarify the function of the PJA1-PGAM5 axis in vivo, we established a xenograft model by implanting control SUNE1 cells or SUNE1 cells with stable PJA1 or PJA1-PGAM5 double knockdown into mice, followed by docetaxel injection, and then monitored tumour growth (Fig. 5g). The gene discussed is PGAM5; the disease is neoplasm.