As expected, maturation markers (e.g. HLA-DR, CD83, CD80 and CD86) on Mo-DCs were upregulated when cocultured with PJA1-knockdown NPC cells, while this effect was abolished when cocultured with PJA1-PGAM5 double-knockdown NPC cells (Fig. 6d). Here, PGAM5 is linked to nasopharyngeal carcinoma.