G3BP1 and esophageal squamous cell carcinoma: ESCC patients with simultaneously high protein levels of USP21 and G3BP1 showed a worse OS and PFS than those with low expression of USP21 and G3BP1 (Fig. 7D, E), with low USP21 and high G3BP1 expression (Fig. 7F, G), or with high USP21 and low G3BP1 expression (Fig. 7H, I).