Abnormal expression of EGFR has a major influence on the growth and development of tumors, and anti-EGFR antibodies have been observed to significantly decrease the number of PN mice.[14] Tyrosine kinase inhibitors can impede the self phosphorylation of EGFR, and abnormal tumor multiplication prevented.[15] HSP90AA1 is a gene that is highly expressed in lung cancer patients and is known to promote squamous cell lung cancer. This evidence concerns the gene HSP90AA1 and neoplasm.