Physical activity is a critical component of primary PCOS management, as it is an effective therapeutic option for the reproductive and metabolic features of the condition.[74,75] Promising evidence supports vigorous aerobic exercise in improving body composition, cardiorespiratory fitness, and insulin resistance.[78] Preliminary data suggests that physically inactive women with PCOS have higher depression scores compared to those who are physically active.[74]. Here, INS is linked to polycystic ovary syndrome.