Sectioning of the dissected tumors at 27 wpf revealed differences in tissue architecture, where the MYCN-TT–derived tumors comprised large amounts of connective tissue and contained smaller foci of cancer cells (Fig. 4E), while MYCN-TT + MOXD1 KO–derived tumors largely consisted of cancer cells (Fig. 4E). Here, MOXD1 is linked to cancer.