We found no significant differences in MOXD1 expression between stages 1/2/3 and stage 4, and localized and metastatic, in colorectal [data previously presented by Marisa et al. (37)] and breast [data previously presented by Cheng et al. (38)] cancer, respectively, which are both cancers believed to arise from nonneural crest lineages (Fig. 1, K and L). The gene discussed is MOXD1; the disease is cancer.