We found that implantation of MOXD1 knockout cells reduced the survival of embryos to 71% (n = 27 of 38) after 2 days (E12) of tumor growth and to as low as 5% (n = 2 of 38) after 4 days (E14; Fig. 3D) as compared to the lack of appreciable effect on survival of the host embryo until after 4 days (E14) and a decrease in viability to 29% (n = 8 of 28) with implantation of control cells (Fig. 3D). This evidence concerns the gene MOXD1 and neoplasm.