Due to the interesting biodistribution data of [18F]F-PSMA-617-NODA obtained in the prostate cancer model (LNCaP), as a proof-of-concept we evaluated the uptake of [18F]F-PSMA-617-NODA also in a glioma model and compared with the uptake of [18F]F-PSMA-617-RESCA. Here, FOLH1 is linked to central nervous system cancer.