ECE1 in the medullary thick ascending limb (M-TAL) was 1.4-fold higher in the LD than AKI men samples and in the glomerular endothelial cells (EC-GC) from LD had a 1.7-fold greater expression of EDNRB compared with CKD samples (Figure 2D). The gene discussed is ECE1; the disease is acute kidney injury.