Hypomethylated CpG sites with significant methylation difference (p<1.0x10–10) in these regions were annotated to the lncRNAs LINC00355, KCNK15-AS1, LOC101928797, LINC00654, and FLG-AS1, LOC100996664, the microRNA mir-6080, the genes CD1D, RGPD2, CDIN1, GXYLT1, PLAGL1, and CHRNE, and the pseudogenes ELL2P1, and CCDC144NL. CD1D (30), GXYLT1 (31), LINC00355 (32), FLG-AS1 (33), CCDC144NL (34), and PLAGL1 (35) have been previously associated with diabetes or diabetes-related complications. This evidence concerns the gene RGPD2 and diabetes mellitus.