Compared to smokers, non-smokers and former smokers have a 50.9% and 56.5% increased odds of IR, respectively (P<0.001).With each unit increase in TG and ALT, the odds of IR increase by 292.2% (P<0.001) and 26% (P<0.001), respectively, while the odds of prediabetes increase by 53.6% and 1% (both P<0.001). Here, GPT is linked to prediabetes syndrome.