Thus, we further analyzed the levels of SEC24A and peIF2α in lymphoma and lymph node of Nlp-/- or Nlp+/- mice respectively, and found that expression levels of both SEC24A and peIF2α were upregulated in lymphoma compared to the normal lymph node, which suggested lymphoma acted more radical in the condition of Nlp deficiency (Fig. 8L). The gene discussed is SEC24A; the disease is lymphoma.