By analyzing the expression level of CPEB1 among the 31 cancer types in The Cancer Genome Atlas (TCGA) database, we found that there are 21 cancer types in which CPEB1 is remarkably less expressed than in the matched tumor-adjacent tissues (Figure S1A), which is consistent with previous reports that CPEB1 is hypermethylated and expressed at low levels in solid tumors 10, 11. The gene discussed is CPEB1; the disease is cancer.