HRH3 and convulsion: These results suggest that the protective effects of H3R antagonist DL76 in the MES-induced convulsions are mediated, at least in part, through an H3R blockade, which is consistent with the formerly observed protective activities of various H3R antagonists (Brigo et al., 2013; Sadek et al., 2014b; Mauritz et al., 2022).