An experimental study (Huang et al., 2022) showed that the H. diffusa injection significantly reduced the survival of lung adenocarcinoma cells in vitro, inhibited the growth of BALB/c nude mice in vivo, and induced iron death of VDAC 2/3 regulation by Bax by inhibiting Bcl-2 gene. The gene discussed is BCL2; the disease is lung adenocarcinoma.