CD44 and neoplasm: In univariate analysis, the death event was associated with heterozygous genotype AG and mutant homozygous genotype GG as compared to wild homozygous genotype AA in CD44 polymorphism rs187115 (p=0.026), ≥ stage II as compared to stage I (p=0.005), > 10 mm as compared to ≤ 10 mm stromal invasion depth (p=0.003), > 4 cm as compared to ≤ 4 cm tumor diameter (p=0.004), positive as compared to negative parameter invasion (p=0.003), and positive as compared to negative pelvic lymph node metastasis (p<0.001; Table 4).