The co-expression patterns in JNU dataset of TXNIP and related genes to evaluate the OS, higher OS was observed in AML patients with low expression of both TXNIP and NLRP3, compared to those with high expression of either gene or both genes, had a better prognosis (1-year OS: TXNIPlowNLRP3low vs. TXNIPhighNLRP3high vs. TXNIPhigh or NLRP3high, 100% vs 25% vs 60%, P = 0.003, Figure 4C). Here, NLRP3 is linked to acute myeloid leukemia.