INS and type 2 diabetes mellitus: Post-exercise plasma glucose and insulin have previously been demonstrated to be improved with low-intensity cycle exercise performed under moderate-to-high hypoxia (∼2000–3,000 m) in individuals with overweight (Tee et al., 2023b; Tee et al., 2023c) and type 2 diabetes (T2D) (Mackenzie et al., 2011; Mackenzie et al., 2012).