As presented in Figure 2, following confounding factor adjustment, a nonlinear association was discovered between MetS risk and several variables, including, the LE8 scores, health behavior scores, health factor scores, phenotype age, circulating Klotho, biological age, SII, DII, HEI, Physical Activity, Smoke, Sleep, BMI, Non-HDL, Glucose, and BP (P-nonlinear <0.001; estimated OR = 1). Here, KL is linked to metabolic syndrome.