In the case of acute retinal detachment, the number of apoptotic photoreceptors was reduced by approximately 50% in TRPV4 knockout mice relative to wild-type mice (Matsumoto et al., 2018), which may be attributable to TRPV4 in photoreceptors more than that expressed (Zhao et al., 2015) in retinal pigment epithelium (RPEs). The gene discussed is TRPV4; the disease is retinal detachment.