Similarly, SNRPN’s role in facial development has been documented, with its dysfunction associated with craniofacial anomalies like mandibulofacial dysostosis Guion-Almeida type and cerebrocostomandibular syndrome (Wood et al., 2019; Alam et al., 2022). The gene discussed is SNRPN; the disease is Cerebro-costo-mandibular syndrome.