LYVE1 and neoplasm: Figure 2 shows typical photographs of intraoperation for nidus of KHEs with KMP. Numerous dark purple thrombi can be seen in the fragile tumor tissue; KHE tissue is positive for CD31, CD34, D2-40, LYVE1, and KI67 on endothelial cells, and GLUT-1 is positive for red blood cells but negative for endothelial cells (Figures 2C–H).