ALOX12 and neoplasm: The RT-qPCR result revealed that ALOX12 was markedly up-regulated (P=0.0144) and RMND5B was markedly down-regulated (P=0.0016) in tumor samples compared with controls, while the expression of CTSC was not notably different (P=0.7259) between tumor and control samples (Figures 10A–C).