Several studies have shown that postoperative PSM in prostate cancer is correlated with post-penetration Gleason score, PSA level, tumor infiltration in seminal vesicles, clinical stage of the tumor, size (volume) of the prostate, proficiency of the surgeon, the age and body mass index of the patient, and biopsy nerve infiltration (18–21). The gene discussed is KLK3; the disease is neoplasm.