HK2 and neoplasm: Tumor cells with elevated arginine levels exhibit significant upregulation of asparagine synthetase (ASNS), phosphoserine aminotransferase 1 (PSAT1), phosphoserine phosphatase (PSPH), and glutaminase kidney isoform (GLSK), while glucose transporter 3 (GLUT3), hexokinase 2 (HK2), NAD+ metabolic gene nicotinamide N‐methyltransferase (NNMT), and primary amine oxidase 3 (AOC3) show an inverse pattern of expression.