Furthermore, in the slices of OV (Figure 3I; Supplementary Figures 11D, I), BRCA (Supplementary Figures 12D, I, N), and CRC (Supplementary Figures 13D, I), a co-localization in the distribution of enriched regions for CD4+ effector T cells gene signature and apCAFs gene signature was noted. The gene discussed is CD4; the disease is colorectal carcinoma.