Our results revealed that collagen synthesis-related genes (e.g., COL1A1, COL1A2, COL3A1, COL4A1, COL5A1, COL5A2, COL6A1, COL6A2, COL6A3, and COL18A1) were upregulated in cancer tissues (Figure 6E). The gene discussed is COL4A1; the disease is cancer.