Additionally, several members of CMGC kinase group including Cyclin-dependent kinase 1 (CDK1), CDK2, Extracellular-signal Regulated Kinase1 (ERK1), ERK2, ERK5, p38-δ, p38-γ, and Alpha-Kinase 1 (AlphaK1), SgK307 are moderately but significantly upregulated after infection with SpnΔlctOΔspxB compared to non-infected cells (Figure 3B). This evidence concerns the gene MAPK1 and infection.