Some of these have reproducible associations with specific antibodies including ovoid palatal patch/verrucous palmar papules/red-on-white patches with anti-TIF1-γ antibodies, calcinosis/edema with anti-NXP-2 antibodies, and inverse/ulcerated Gottron papules and anti-MDA5 antibodies (2–5, 15). Here, IFIH1 is linked to calcinosis.