SNRNP70 and systemic lupus erythematosus: However, the neurological manifestations in lupus are more common, and neuroimaging can reveal small vessel to large vessel and subcortical lesions, meningeal enhancement, etc. Thus, aseptic meningitis with the specific U1-RNP antibodies tilts the diagnosis in favor of MCTD, rules out drug-induced causes, and also adds to the prognostic value.