ITGA5 and colorectal cancer: Numerous studies have shown that the overexpression of ITGA5 is linked to unfavorable outcomes in various types of tumors, including triple-negative breast cancer (Xiao et al., 2018), ovarian cancer (Gong et al., 2016), colorectal cancer (Yu et al., 2019) and lung cancer (Zheng et al., 2016).