In the regulation of inflammation, HOXA11-AS mediated CaOx crystal-induced renal inflammation via the miR-124-3p/MCP-1 axis [41], while inhibition of HOXA11-AS repressed neuroinflammation and neuronal apoptosis in Parkinson’s disease model through through miR-124-3p-FSTL1-NF-κB axis [42] and miR-98-5p/EphA4 [43]. Here, CCL2 is linked to Parkinson disease.