The genes associated with the scores of BM and VM in the classification model can be found in Supplementary Fig. 2 and some genes are knowingly associated with infections, such as ASRGL1, NR2F6, and OLFML3 for bacterial infection (Fig. 4E) and STIP1, PGAM5, and AKAP8 for viral infections (Fig. 4F). This evidence concerns the gene AKAP8 and viral infectious disease.