IGF1 and acromegaly: Dopamine-agonists (DA) represent the first line treatment in patients with hyperprolactinemia; however, they can be also used in acromegaly, As a result, patients with acromegaly may be misdiagnosed or receive a late diagnosis, although the prevalence of silent acromegaly seems to be very low [2] On the other hand it has been reported that DA can cause an increase of the IGF-1 levels [3].