Similarly, Zhu et al. found that clear cell renal carcinoma (CCRC) cells secrete the long non-coding RNA (lncRNA) DMDRMR, which acts as a sponge for miR-378a-5p, and indirectly causes DAB2IP downregulation in receiving cells; this correlates with enhanced VEGFA/VEGFR2 signaling and increased tube formation by HUVECs [53]. This evidence concerns the gene DAB2IP and clear cell renal carcinoma.