HLA-E and Miyoshi myopathy: The expression of HLA-E and other IFN-γ related genes in MM highlights the presence of an immune phenotype in a proportion of patients with MM, which is further triggered and maintained by immunomodulatory drugs; CREB1 inhibition was able to exploit this phenotype potentiating the effect of pomalidomide in the presence of NK cells, without affecting NK cell viability.